Endocrine Abstracts

Objective: To determine the factors influencing the level of knowledge and attitudes of diabetics consulting in first and third line in the Sousse region (Tunisia).Patients and Methods: We undertook a cross-sectional study. Diabetics were included by proportional sampling in 11 basic health centers and six hospital departments and outpatient clinics of the university hospital centers of Sousse. The developed questionnaire was self-administered in Arabic....

Objective: This study aimed to translate into Arabic and validate the questionnaires "Simplified Diabetes Knowledge Scale" (SDKS), "Diabetes Attitude Scale-3" (DAS-3) and "Diabetes Health Profile-18" (DHP-18) and to study the predictive factors of the level of knowledge, attitudes and quality of life of diabetics in the health region of Sousse.Population and Methods: A methodological study of psychometric validation was carried ou...

Klinefelter syndrome (KS) is the most frequent sex chromosomal disorder and affects approximately one in 660 newborn boys. The phenotype is variable ranging from ‘nearnormal’ to a significantly affected individual. Typically, diagnosis is delayed with the majority of patients identified during fertility workup in adulthood, and only 10% of patients diagnosed prior to puberty.Patients and methods: This is an 8-year retrospective study of the cli...

Introduction: Sheehan syndrome (SS), or postpartum pituitary necrosis, is a complete or dissociated adeno-pituitary insufficiency due to hypovolemia secondary to excessive blood loss during or after delivery. Although few studies have investigated osteoporosis in isolated hormone deficiencies, the relationship between SS and osteoporosis has not been investigated in large series of SS. In this study, we aimed to evaluate bone mineral density (BMD) in patients with SS.<p cl...

Introduction: Acromegaly is a rare hormonal condition that results from an excess amount of growth hormone (GH) in the body. A variety of complications have been reported in patients with acromegaly including cardiovascular diseases, diabetes mellitus or respiratory disorders. In addition, Acromegaly is associated with gastrointestinal complications. The aim of this study was to evaluate gastrointestinal complications and their impact on the quality of life among patients suff...

Introduction: Sheehan Syndrome (SS) is the oldest known cause of non-tumor acquired anterior pituitary insufficiency in women. The incidence of SS would probably have decreased in recent decades in developed countries thanks to the development of obstetric care. However, it still remains a public health problem in developing countries. In addition, it constitutes a chronic disabling pathology and is strongly linked to an alteration of the quality of life. In this study we aime...

Introduction: Sheehan syndrome has been for a long time the most frequent cause of hypopituitarism among women in developing countries, including Tunisia. Apart from hormonal deficits caused by SS, young women with SS are exposed to an increased risk of cardiovascular mortality. In this study, we aimed to evaluate the cardiovascular risk in patients with SS. Patients and methods This is a descriptive cross-sectional study. It was carried out in the Endocrinology department of ...

Introduction: Primary hyperparathyroidism (PHPT) is most commonly sporadic and in rare circumstances, it can develop as part of multiple endocrine neoplasia (MEN). There are few cases described in the literature reporting an association of PHPT with myasthenia gravis and multiple autoimmune syndrome (MAS). These patients may present only with clinical signs of PHPT making it difficult to suspect the coexistence of MAS. Here, we report the case of type 3 MAS in a woman with PHP...

Introduction: Thyrotropin deficiency is a rare etiology of hypothyroidism. The diagnosis can be easily confirmed in case of low FT4 level associated with normal or low TSH value. In patients with peripheral hypothyroidism treated by levothyroxine, this biochemical profile become difficult to find. Herein, we describe the case of a patient with peripheral hypothyroidism due to radioiodine therapy in whom the diagnosis of central hypothyroidism was made.Ob...

Introduction: Neurofibromatosis type 1 (NF1) is a rare autosomal dominant disease. Patients affected by NF1 have an increased risk of developing tumors other than neurofibromas, especially of endocrine origin, that’s why this patients should be screened for endocrine lesions. In this report, we describe a patient affected by NF1 who present a thyroid nodule.Observation: A 27-year-old woman was admitted in our department for endocrinological evaluati...